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Ubiquitylation of FACT by the Cullin-E3 ligase Rtt101 connects FACT to DNA replication

FACT plays important roles in both gene transcription and DNA replication. However, how this protein complex is targeted to these two distinct cellular processes remains largely unknown. Here we show that ubiquitylation of the Spt16 subunit of FACT by Rtt101, the cullin subunit of an E3 ubiquitin li...

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Detalhes bibliográficos
Main Authors: Han, Junhong, Li, Qing, McCullough, Laura, Kettelkamp, Charisse, Formosa, Tim, Zhang, Zhiguo
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904938/
https://ncbi.nlm.nih.gov/pubmed/20634314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1887310
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