Ronin/Hcf-1 binds to a hyperconserved enhancer element and regulates genes involved in the growth of embryonic stem cells

Self-renewing embryonic stem (ES) cells have an exceptional need for timely biomass production, yet the transcriptional control mechanisms responsible for meeting this requirement are largely unknown. We report here that Ronin (Thap11), which is essential for the self-renewal of ES cells, binds with...

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Autori principali: Dejosez, Marion, Levine, Stuart S., Frampton, Garrett M., Whyte, Warren A., Stratton, Sabrina A., Barton, Michelle C., Gunaratne, Preethi H., Young, Richard A., Zwaka, Thomas P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2010
Soggetti:
Research Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904937/
https://ncbi.nlm.nih.gov/pubmed/20581084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1935210
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