CHD7 Targets Active Gene Enhancer Elements to Modulate ES Cell-Specific Gene Expression

CHD7 is one of nine members of the chromodomain helicase DNA–binding domain family of ATP–dependent chromatin remodeling enzymes found in mammalian cells. De novo mutation of CHD7 is a major cause of CHARGE syndrome, a genetic condition characterized by multiple congenital anomalies. To gain insight...

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Detalhes bibliográficos
Main Authors: Schnetz, Michael P., Handoko, Lusy, Akhtar-Zaidi, Batool, Bartels, Cynthia F., Pereira, C. Filipe, Fisher, Amanda G., Adams, David J., Flicek, Paul, Crawford, Gregory E., LaFramboise, Thomas, Tesar, Paul, Wei, Chia-Lin, Scacheri, Peter C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904778/
https://ncbi.nlm.nih.gov/pubmed/20657823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001023
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