A novel trifunctional IgG-like bispecific antibody to inhibit HIV-1 infection and enhance lysis of HIV by targeting activation of complement

BACKGROUND: The complement system is not only a key component of innate immunity but also provides a first line of defense against invading pathogens, especially for viral pathogens. Human immunodeficiency virus (HIV), however, possesses several mechanisms to evade complement-mediated lysis (CoML) a...

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Detalhes bibliográficos
Main Authors: Jia, Leili, Xu, Yuanyong, Zhang, Chuanfu, Wang, Yong, Chong, Huihui, Qiu, Shaofu, Wang, Ligui, Zhong, Yanwei, Liu, Weijing, Sun, Yansong, Qiao, Fei, Tomlinson, Stephen, Song, Hongbin, Zhou, Yusen, He, Yuxian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Hypothesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904741/
https://ncbi.nlm.nih.gov/pubmed/20584336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-7-142
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