An insertion mutation in ABCB4 is associated with gallbladder mucocele formation in dogs

BACKGROUND: ABCB4 functions as a phosphatidylcholine translocater, flipping phosphatidylcholine across hepatocyte canalicular membranes into biliary canaliculi. In people, ABCB4 gene mutations are associated with several disease syndromes including intrahepatic cholestasis of pregnancy, progressive...

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Autores principales: Mealey, Katrina L, Minch, Jonathan D, White, Stephen N, Snekvik, Kevin R, Mattoon, John S
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904718/
https://ncbi.nlm.nih.gov/pubmed/20598156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-5926-9-6
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