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Myc proteins as therapeutic targets

Myc proteins (c-myc, Mycn and Mycl) target proliferative and apoptotic pathways vital for progression in cancer. Amplification of the MYCN gene has emerged as one of the clearest indicators of aggressive and chemotherapy-refractory disease in children with neuroblastoma, the most common extracranial...

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Autors principals: Gustafson, WC, Weiss, WA
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904682/
https://ncbi.nlm.nih.gov/pubmed/20101214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.512
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