Ischaemic preconditioning-regulated miR-21 protects heart against ischaemia/reperfusion injury via anti-apoptosis through its target PDCD4

AIMS: The aims of the present study are to determine the miRNA expression signature in rat hearts after ischaemic preconditioning (IP) and to identify an IP-regulated miRNA, miR-21, in IP-mediated cardiac protection, and the potential cellular and molecular mechanisms involved. METHODS AND RESULTS:...

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Autors principals: Cheng, Yunhui, Zhu, Ping, Yang, Jian, Liu, Xiaojun, Dong, Shimin, Wang, Xiaobin, Chun, Bao, Zhuang, Jian, Zhang, Chunxiang
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904662/
https://ncbi.nlm.nih.gov/pubmed/20219857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvq082
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