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Constitutive glycogen synthase kinase-3α/β activity protects against chronic β-adrenergic remodelling of the heart

AIMS: Glycogen synthase kinase 3 (GSK-3) signalling is implicated in the growth of the heart during development and in response to stress. However, its precise role remains unclear. We set out to characterize developmental growth and response to chronic isoproterenol (ISO) stress in knockin (KI) mic...

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書誌詳細
主要な著者: Webb, Ian G., Nishino, Yasuhiro, Clark, James E., Murdoch, Colin, Walker, Simon J., Makowski, Marcus R., Botnar, Rene M., Redwood, Simon R., Shah, Ajay M., Marber, Michael S.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2010
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904659/
https://ncbi.nlm.nih.gov/pubmed/20299330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvq061
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