Discrete Roles of STAT4 and STAT6 transcription factors in Tuning Epigenetic Modifications and Transcription during Helper T Cell Differentiation

Signal transducer and activator of transcription 4 (STAT4) and STAT6 are key factors in the specification of helper T cells; however, their direct roles in driving differentiation are not well understood. Using chromatin immunoprecipitation and massive parallel sequencing, we quantitated the full co...

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Hauptverfasser: Wei, Lai, Vahedi, Golnaz, Sun, Hong-Wei, Watford, Wendy T., Takatori, Hiroaki, Ramos, Haydee L., Takahashi, Hayato, Liang, Jonathan, Gutierrez-Cruz, Gustavo, Zang, Chongzhi, Peng, Weiqun, O'Shea, John J., Kanno, Yuka
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904651/
https://ncbi.nlm.nih.gov/pubmed/20620946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.06.003
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