Left ventricular hypertrophy and diastolic dysfunction in children with sickle cell disease are related to asleep and waking oxygen desaturation

Premature death and cardiac abnormalities are described in individuals with sickle cell disease (SCD), but the mechanisms are not well characterized. We tested the hypothesis that cardiac abnormalities in children with SCD are related to sleep-disordered breathing. We enrolled 44 children with SCD (...

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Bibliografiske detaljer
Main Authors: Johnson, Mark C., Kirkham, Fenella J., Redline, Susan, Rosen, Carol L., Yan, Yan, Roberts, Irene, Gruenwald, Jeanine, Marek, Jan, DeBaun, Michael R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2010
Fag:
Clinical Trials and Observations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904578/
https://ncbi.nlm.nih.gov/pubmed/20378754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-06-227447
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