A cembranoid from tobacco prevents the expression of nicotine-induced withdrawal behavior in planarian worms

Using an adaptation of published behavioral protocols, we determined that acute exposure to the cholinergic compounds nicotine and carbamylcholine decreased planarian motility in a concentration-dependent manner. A tobacco cembranoid (1S,2E,4R,6R,7E,11E)-cembra-2,7,11-triene-4,6-diol (4R-cembranoid)...

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Main Authors: Pagán, Oné R., Rowlands, Amanda L., Fattore, Angela L., Coudron, Tamara, Urban, Kimberly R., Bidja, Apurva H., Eterović, Vesna A.
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904570/
https://ncbi.nlm.nih.gov/pubmed/19490913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2009.05.022
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