Transmembrane Signaling by the Aspartate Receptor: Engineered Disulfides Reveal Static Regions of the Subunit Interface

Ligand binding to the periplasmic domain of the transmembrane aspartate receptor generates an intramolecular conformational change which spans the bilayer and ultimately signals the cytoplasmic CheA histidine kinase, thereby triggering chemotaxis. The receptor is a homodimer stabilized by the interf...

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Hauptverfasser: Chervitz, Stephen A., Lin, Christina M., Falke, Joseph J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1995
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904562/
https://ncbi.nlm.nih.gov/pubmed/7626643
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