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Inhibition of striatal dopamine release by CB1 receptor activation requires nonsynaptic communication involving GABA, H(2)O(2), and K(ATP) channels
The main psychoactive component of marijuana, Δ(9)-tetrahydrocannabinol (THC), acts in the CNS via type 1 cannabinoid receptors (CB1Rs). The behavioral consequences of THC or synthetic CB1R agonists include suppression of motor activity. One explanation for movement suppression might be inhibition o...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2904528/ https://ncbi.nlm.nih.gov/pubmed/17767979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2007.07.014 |
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