Omega-3 and omega-6 fatty acids suppress ER- and oxidative-stress in cultured neurons and neuronal progenitor cells from mice lacking PPT1

Reactive oxygen species (ROS) damage to brain lipids, carbohydrates, proteins, and DNA may contribute to neurodegeneration. We previously reported that ER- and oxidative stress cause neuronal apoptosis in infantile neuronal ceroid lipofuscinosis (INCL), a lethal neurodegenerative storage disease, ca...

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Sonraí Bibleagrafaíochta
Main Authors: Kim, Sung-Jo, Zhang, Zhongjian, Saha, Arjun, Sarkar, Chinmoy, Zhao, Zhenwen, Xu, Yan, Mukherjee, Anil B.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904481/
https://ncbi.nlm.nih.gov/pubmed/20561933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2010.05.083
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