LRP-1 Promotes Cancer Cell Invasion by Supporting ERK and Inhibiting JNK Signaling Pathways

BACKGROUND: The low-density lipoprotein receptor-related protein-1 (LRP-1) is an endocytic receptor mediating the clearance of various extracellular molecules involved in the dissemination of cancer cells. LRP-1 thus appeared as an attractive receptor for targeting the invasive behavior of malignant...

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Bibliographic Details
Main Authors: Langlois, Benoit, Perrot, Gwenn, Schneider, Christophe, Henriet, Patrick, Emonard, Hervé, Martiny, Laurent, Dedieu, Stéphane
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904376/
https://ncbi.nlm.nih.gov/pubmed/20644732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011584
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