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Early life stress downregulates endothelin receptor expression and enhances acute stress-mediated blood pressure responses in adult rats
We hypothesized that early life stress enhances endothelin (ET-1)-dependent acute stress responses in adulthood. We utilized a unique rat model, wild-type (WT) and ET(B) receptor-deficient spotting lethal (sl/sl) rats, as well as pharmacological blockade of ET receptors, in a model of early life str...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2904153/ https://ncbi.nlm.nih.gov/pubmed/20410476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00333.2009 |
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