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Overexpression of HSP10 in skeletal muscle of transgenic mice prevents the age-related fall in maximum tetanic force generation and muscle cross-sectional area

Skeletal muscle atrophy and weakness are major contributors to frailty and impact significantly on quality of life of older people. Muscle aging is characterized by a loss of maximum tetanic force (P(o)) generation, primarily due to muscle atrophy, to which mitochondrial dysfunction is hypothesized...

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Detalhes bibliográficos
Main Authors: Kayani, Anna C., Close, Graeme L., Dillmann, Wolfgang H., Mestril, Ruben, Jackson, Malcolm J., McArdle, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904147/
https://ncbi.nlm.nih.gov/pubmed/20410481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00334.2009
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