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LATS1 phosphorylates forkhead L2 and regulates its transcriptional activity

Forkhead L2 (FOXL2) is expressed in the ovary and acts as a transcriptional repressor of the steroidogenic acute regulatory (StAR) gene, a marker of granulosa cell differentiation. Human FOXL2 mutations that produce truncated proteins lacking the COOH terminus result in blepharophimosis/ptosis/epica...

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Bibliographic Details
Main Authors: Pisarska, Margareta D., Kuo, Fang-Ting, Bentsi-Barnes, Ikuko K., Khan, Salma, Barlow, Gillian M.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904049/
https://ncbi.nlm.nih.gov/pubmed/20407010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00534.2009
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