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Molecular genetic analysis of the orsellinic acid/F9775 gene cluster of Aspergillus nidulans

F-9775A and F-9775B are cathepsin K inhibitors that arise from a chromatin remodelling deletant strain of Aspergillus nidulans. A polyketide synthase gene has been determined to be responsible for their formation and for the simpler, archetypical polyketide orsellinic acid. We have discovered simple...

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Detalhes bibliográficos
Main Authors: Sanchez, James F., Chiang, Yi-Ming, Szewczyk, Edyta, Davidson, Ashley D., Ahuja, Manmeet, Oakley, C. Elizabeth, Bok, Jin Woo, Keller, Nancy, Oakley, Berl R., Wang, Clay C. C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903553/
https://ncbi.nlm.nih.gov/pubmed/20174687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b904541d
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