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Hyperinsulinemia improves ischemic LV function in insulin resistant subjects

BACKGROUND: Glucose is a more efficient substrate for ATP production than free fatty acid (FFA). Insulin resistance (IR) results in higher FFA concentrations and impaired myocardial glucose use, potentially worsening ischemia. We hypothesized that metabolic manipulation with a hyperinsulinemic eugly...

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Bibliografische gegevens
Hoofdauteurs: Heck, Patrick M, Hoole, Stephen P, Khan, Sadia N, Dutka, David P
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903514/
https://ncbi.nlm.nih.gov/pubmed/20576156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-9-27
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