In Vitro and In Vivo High-Throughput Assays for the Testing of Anti-Trypanosoma cruzi Compounds

BACKGROUND: The two available drugs for treatment of T. cruzi infection, nifurtimox and benznidazole (BZ), have potential toxic side effects and variable efficacy, contributing to their low rate of use. With scant economic resources available for antiparasitic drug discovery and development, inexpen...

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Autori principali: Canavaci, Adriana M. C., Bustamante, Juan M., Padilla, Angel M., Perez Brandan, Cecilia M., Simpson, Laura J., Xu, Dan, Boehlke, Courtney L., Tarleton, Rick L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903469/
https://ncbi.nlm.nih.gov/pubmed/20644616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000740
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