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Uptake of Foreign Nucleic Acids in Kidney Tubular Epithelial Cells Deficient in Proapoptotic Endonucleases

Degradation of DNA during gene delivery is an obstacle for gene transfer and for gene therapy. DNases play a major role in degrading foreign DNA. However, which of the DNases are involved and whether their inactivation can improve gene delivery have not been studied. We have recently identified deox...

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Detalhes bibliográficos
Main Authors: Buzder, Timea, Yin, Xiaoyan, Wang, Xiaoying, Banfalvi, Gaspar, Basnakian, Alexei G.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903456/
https://ncbi.nlm.nih.gov/pubmed/19558214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dna.2008.0850
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