Polyethylene glycol-based homologated ligands for nicotinic acetylcholine receptors

A homologous series of polyethylene glycol (PEG) monomethyl ethers were conjugated with three ligand series for nicotinic acetylcholine receptors. Conjugates of acetylaminocholine, the cyclic analog 1-acetyl-4,4-dimethylpiperazinium, and pyridyl ether A-84543 were prepared. Each series was found to...

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Autori principali: Scates, Bradley A., Lashbrook, Bethany L., Chastain, Benjamin C., Tominaga, Kaoru, Elliott, Brandon T., Theising, Nicholas J., Baker, Thomas A., Fitch, Richard W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903455/
https://ncbi.nlm.nih.gov/pubmed/19006672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.10.045
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