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Binding of Imidazole to the Heme of Cytochrome c(1) and Inhibition of the bc(1) Complex from Rhodobacter sphaeroides: I. EQUILIBRIUM AND MODELING STUDIES

We have used imidazole (Im) and N-methylimidazole (MeIm) as probes of the heme-binding cavity of membrane-bound cytochrome (cyt) c(1) in detergent-solubilized bc(1) complex from Rhodobacter sphaeroides. Imidazole binding to cyt c(1) substantially lowers the midpoint potential of the heme and fully i...

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Hlavní autoři: Kokhan, Oleksandr, Shinkarev, Vladimir P., Wraight, Colin A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903416/
https://ncbi.nlm.nih.gov/pubmed/20448035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.128058
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