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A Toxin-based Probe Reveals Cytoplasmic Exposure of Golgi Sphingomyelin

Although sphingomyelin is an important cellular lipid, its subcellular distribution is not precisely known. Here we use a sea anemone cytolysin, equinatoxin II (EqtII), which specifically binds sphingomyelin, as a new marker to detect cellular sphingomyelin. A purified fusion protein composed of Eqt...

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Bibliografski detalji
Glavni autori: Bakrač, Biserka, Kladnik, Aleš, Maček, Peter, McHaffie, Gavin, Werner, Andreas, Lakey, Jeremy H., Anderluh, Gregor
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903383/
https://ncbi.nlm.nih.gov/pubmed/20463009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.105122
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