Inhibition of Hepatitis B Virus Replication by MyD88 Involves Accelerated Degradation of Pregenomic RNA and Nuclear Retention of Pre-S/S RNAs

Myeloid differentiation primary response protein 88 (MyD88), which can be induced by alpha interferon (IFN-α), has an antiviral activity against the hepatitis B virus (HBV). The mechanism of this antiviral activity remains poorly understood. Here, we report that MyD88 inhibited HBV replication in He...

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Bibliografiske detaljer
Main Authors: Li, Jianhua, Lin, Shanshan, Chen, Qiying, Peng, Lu, Zhai, Jianwei, Liu, Yinghui, Yuan, Zhenghong
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Genome Replication and Regulation of Viral Gene Expression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903248/
https://ncbi.nlm.nih.gov/pubmed/20410269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00236-10
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