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Computing the conformational entropy for RNA folds

We develop a polymer physics-based method to compute the conformational entropy for RNA tertiary folds, namely, conformations consisting of multiple helices connected through (cross-linked) loops. The theory is based on a virtual bond conformational model for the nucleotide chain. A key issue in the...

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Autors principals: Liu, Liang, Chen, Shi-Jie
Format: Artigo
Idioma:Inglês
Publicat: American Institute of Physics 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903186/
https://ncbi.nlm.nih.gov/pubmed/20572741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3447385
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