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The N-terminus of Glycogen Phosphorylase b is Not Required for Activation by AMP

The, so far unsuccessful, search for selective effective inhibitors of glycogen phosphorylase for the treatment of type II diabetes has made phosphorylase an active target of research for the last twenty years. Many crystallographic structures of phosphorylase are currently available to aid in this...

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Autors principals: Bigley, Andrew N., Reinhart, Gregory D.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902993/
https://ncbi.nlm.nih.gov/pubmed/20420452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9020555
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