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Structural and Functional Changes in the αA-Crystallin R116C Mutant in Hereditary Cataracts
α-Crystallin, the major protein component of vertebrate lenses, forms a large complex comprised of two homologous subunits, αA- and αB-crystallin. It has the ability to suppress stress-induced protein aggregation in vitro, bind saturably to lens plasma membranes, and aid in light refraction through...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2902970/ https://ncbi.nlm.nih.gov/pubmed/11123904 |
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