Radiation Exposure, the ATM Gene, and Contralateral Breast Cancer in the Women's Environmental Cancer and Radiation Epidemiology Study

BACKGROUND: Ionizing radiation is a known mutagen and an established breast carcinogen. The ATM gene is a key regulator of cellular responses to the DNA damage induced by ionizing radiation. We investigated whether genetic variants in ATM play a clinically significant role in radiation-induced contr...

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Main Authors: Bernstein, Jonine L., Haile, Robert W., Stovall, Marilyn, Boice, John D., Shore, Roy E., Langholz, Bryan, Thomas, Duncan C., Bernstein, Leslie, Lynch, Charles F., Olsen, Jorgen H., Malone, Kathleen E., Mellemkjaer, Lene, Borresen-Dale, Anne-Lise, Rosenstein, Barry S., Teraoka, Sharon N., Diep, Anh T., Smith, Susan A., Capanu, Marinela, Reiner, Anne S., Liang, Xiaolin, Gatti, Richard A., Concannon, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902825/
https://ncbi.nlm.nih.gov/pubmed/20305132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djq055
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