Replacement of Rbpj with Rbpjl in the PTF1 complex controls the final maturation of pancreatic acinar cells

BACKGROUND & AIMS: The mature pancreatic acinar cell is dedicated to the production of very large amounts of digestive enzymes. The early stages of pancreatic development require the Rbpj-form of the trimeric transcription factor complex PTF1 (PTF1-J). As acinar development commences, Rbpjl grad...

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Main Authors: Masui, Toshihiko, Swift, Galvin H., Deering, Tye, Shen, Chengcheng, Coats, Ward S., Long, Qiaoming, Elsässer, Hans-Peter, Magnuson, Mark A., MacDonald, Raymond J.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902682/
https://ncbi.nlm.nih.gov/pubmed/20398665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.04.003
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