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HLA-B alleles associate consistently with HIV heterosexual transmission, viral load and progression to AIDS, but not susceptibility to infection

OBJECTIVE: HLA class I polymorphism is known to affect the rate of progression to AIDS after infection with HIV-1. Here we test the consistency of HLA-B allelic effects on progression to AIDS, heterosexual HIV transmission and ‘setpoint’ viral levels. METHODS: We used adjusted Cox proportional hazar...

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Detalhes bibliográficos
Main Authors: Gao, Xiaojiang, O'Brien, Thomas R., Welzel, Tania M., Marti, Darlene, Qi, Ying, Goedert, James J., Phair, John, Pfeiffer, Ruth, Carrington, Mary
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902625/
https://ncbi.nlm.nih.gov/pubmed/20588164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e32833c3219
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