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Mutating the converter-relay interface of Drosophila myosin perturbs ATPase activity, actin motility, myofibril stability and flight ability

We used an integrative approach to probe the significance of the interaction between the relay loop and converter domain of the myosin molecular motor from Drosophila melanogaster indirect flight muscle. During the myosin mechanochemical cycle, ATP-induced twisting of the relay loop is hypothesized...

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Autori principali: Kronert, William A., Melkani, Girish C., Melkani, Anju, Bernstein, Sanford I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902547/
https://ncbi.nlm.nih.gov/pubmed/20362584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.03.049
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