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Geranylgeranyltransferase I is essential for dendritic development of cerebellar Purkinje cells

BACKGROUND: During cerebellar development, Purkinje cells (PCs) form the most elaborate dendritic trees among neurons in the brain, but the mechanism regulating PC arborization remains largely unknown. Geranylgeranyltransferase I (GGT) is a prenyltransferase that is responsible for lipid modificatio...

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Détails bibliographiques
Auteurs principaux: Wu, Kong-Yan, Zhou, Xiu-Ping, Luo, Zhen-Ge
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902468/
https://ncbi.nlm.nih.gov/pubmed/20540740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-3-18
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