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Development and Statistical Optimization of Solid Lipid Nanoparticles of Simvastatin by Using 2(3) Full-Factorial Design
The objective of this study was to develop solid lipid nanoparticles (SLNs) of simvastatin and to optimize it for independent variables (amount of glycerol monostearate, concentration of poloxamer, and volume of isopropyl alcohol) in order to achieve desired particle size with maximum percent entrap...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2902350/ https://ncbi.nlm.nih.gov/pubmed/20309652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9414-z |
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