Investigation of the Physicochemical and Physicomechanical Properties of a Novel Intravaginal Bioadhesive Polymeric Device in the Pig Model

The purpose of this study was to develop and evaluate the bioadhesivity, in vitro drug release, and permeation of an intravaginal bioadhesive polymeric device (IBPD) loaded with 3′-azido-3′-deoxythymidine (AZT) and polystyrene sulfonate (PSS). Modified polyamide 6,10, poly(lactic-coglycolic acid), p...

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Main Authors: Ndesendo, Valence M. K., Pillay, Viness, Choonara, Yahya E., du Toit, Lisa C., Buchmann, Eckhart, Meyer, Leith C. R., Khan, Riaz A., Rosin, Uwe
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902328/
https://ncbi.nlm.nih.gov/pubmed/20446071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9439-3
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