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In vitro Permeability Enhancement in Intestinal Epithelial Cells (Caco-2) Monolayer of Water Soluble Quaternary Ammonium Chitosan Derivatives

The aim of this study was to investigate the effects of a type of hydrophobic moiety, extent of N-substitution (ES), and degree of quaternization (DQ) of chitosan (CS) on the transepithelial electrical resistance and permeability of Caco-2 cells monolayer, using fluorescein isothiocyanate dextran 4,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kowapradit, Jariya, Opanasopit, Praneet, Ngawhirunpat, Tanasait, Apirakaramwong, Auayporn, Rojanarata, Theerasak, Ruktanonchai, Uracha, Sajomsang, Warayuth
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902307/
https://ncbi.nlm.nih.gov/pubmed/20333490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9399-7
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