Sustained Liver Targeting and Improved Antiproliferative Effect of Doxorubicin Liposomes Modified with Galactosylated Lipid and PEG-Lipid

In this study, a cleavable PEG-lipid (methoxypolyethyleneglycol 2000-cholesteryl hemisuccinate, PEG(2000)-CHEMS) linked via ester bond and galactosylated lipid ((5-cholesten-3β-yl) 4-oxo-4-[2-(lactobionyl amido) ethylamido] butanoate, CHS-ED-LA) were used to modify doxorubicin (DOX) liposome. DOX wa...

Full description

Saved in:
Bibliographic Details
Main Authors: Wang, Shaoning, Xu, Hui, Xu, Jinghua, Zhang, Ying, Liu, Yingchun, Deng, Yi-hui, Chen, Dawei
Format: Artigo
Language:Inglês
Published: Springer US 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902302/
https://ncbi.nlm.nih.gov/pubmed/20490957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9450-8
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items