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Formulation of Ketotifen Fumarate Fast-Melt Granulation Sublingual Tablet

The purpose of this study was to prepare sublingual tablets, containing the antiasthmatic drug ketotifen fumarate which suffers an extensive first-pass effect, using the fast-melt granulation technique. The powder mixtures containing the drug were agglomerated using a blend of polyethylene glycol 40...

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Detalhes bibliográficos
Main Authors: Tayel, Saadia A., Soliman, Iman I., Louis, Dina
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902300/
https://ncbi.nlm.nih.gov/pubmed/20407934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9425-9
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