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A model for familial exudative vitreoretinopathy caused by LPR5 mutations

We have identified a mouse recessive mutation that leads to attenuated and hyperpermeable retinal vessels, recapitulating some pathological features of familial exudative vitreoretinopathy (FEVR) in human patients. DNA sequencing reveals a single nucleotide insertion in the gene encoding the low-den...

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Detalhes bibliográficos
Main Authors: Xia, Chun-Hong, Liu, Haiquan, Cheung, Debra, Wang, Meng, Cheng, Catherine, Du, Xin, Chang, Bo, Beutler, Bruce, Gong, Xiaohua
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902293/
https://ncbi.nlm.nih.gov/pubmed/18263894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn047
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