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New Targeted Molecular Therapies for Dedifferentiated Thyroid Cancer

Dedifferentiated thyroid cancer (DeTC) derived from follicular epithelium is often incurable because it does not respond to radioiodine, radiotherapy, or chemotherapy. In cases, RET/PTC rearrangements are found in 30%–40%, RAS mutations in about 10%, and BRAF mutations in around 40%–50%, with no ove...

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Detalhes bibliográficos
Main Authors: Antonelli, Alessandro, Ferri, Clodoveo, Ferrari, Silvia Martina, Sebastiani, Marco, Colaci, Michele, Ruffilli, Ilaria, Fallahi, Poupak
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902220/
https://ncbi.nlm.nih.gov/pubmed/20628483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/921682
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