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Perturbation of single hematopoietic stem cell fates in artificial niches

Hematopoietic stem cells (HSCs) are capable of extensive self-renewal in vivo and are successfully employed clinically to treat hematopoietic malignancies, yet are in limited supply as in culture this self-renewal capacity is lost. Using an approach at the interface of stem cell biology and bioengin...

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Detalhes bibliográficos
Main Authors: Lutolf, Matthias P., Doyonnas, Regis, Havenstrite, Karen, Koleckar, Kassie, Blau, Helen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902161/
https://ncbi.nlm.nih.gov/pubmed/20023792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b815718a
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