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Muscle channelopathies: does the predicted channel gating pore offer new treatment insights for hypokalaemic periodic paralysis?
Hypokalaemic periodic paralysis (hypoPP) is the archetypal skeletal muscle channelopathy caused by dysfunction of one of two sarcolemmal ion channels, either the sodium channel Nav1.4 or the calcium channel Cav1.1. Clinically, hypoPP is characterised by episodes of often severe flaccid muscle paraly...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Blackwell Science Inc
2010
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2901976/ https://ncbi.nlm.nih.gov/pubmed/20123788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.186627 |
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