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Isocitrate Dehydrogenase Is Important for Nitrosative Stress Resistance in Cryptococcus neoformans, but Oxidative Stress Resistance Is Not Dependent on Glucose-6-Phosphate Dehydrogenase

The opportunistic intracellular fungal pathogen Cryptococcus neoformans depends on many antioxidant and denitrosylating proteins and pathways for virulence in the immunocompromised host. These include the glutathione and thioredoxin pathways, thiol peroxidase, cytochrome c peroxidase, and flavohemog...

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Bibliografski detalji
Glavni autori: Brown, Sarah M., Upadhya, Rajendra, Shoemaker, James D., Lodge, Jennifer K.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901651/
https://ncbi.nlm.nih.gov/pubmed/20400467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00271-09
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