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Isocitrate Dehydrogenase Is Important for Nitrosative Stress Resistance in Cryptococcus neoformans, but Oxidative Stress Resistance Is Not Dependent on Glucose-6-Phosphate Dehydrogenase

The opportunistic intracellular fungal pathogen Cryptococcus neoformans depends on many antioxidant and denitrosylating proteins and pathways for virulence in the immunocompromised host. These include the glutathione and thioredoxin pathways, thiol peroxidase, cytochrome c peroxidase, and flavohemog...

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Detalhes bibliográficos
Main Authors: Brown, Sarah M., Upadhya, Rajendra, Shoemaker, James D., Lodge, Jennifer K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901651/
https://ncbi.nlm.nih.gov/pubmed/20400467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00271-09
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