A Plasmodium falciparum Transcriptional Cyclin-Dependent Kinase-Related Kinase with a Crucial Role in Parasite Proliferation Associates with Histone Deacetylase Activity

Cyclin-dependent protein kinases (CDKs) are key regulators of the eukaryotic cell cycle and of the eukaryotic transcription machinery. Here we report the characterization of Pfcrk-3 (Plasmodium falciparum CDK-related kinase 3; PlasmoDB identifier PFD0740w), an unusually large CDK-related protein who...

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Главные авторы: Halbert, Jean, Ayong, Lawrence, Equinet, Leila, Le Roch, Karine, Hardy, Mary, Goldring, Dean, Reininger, Luc, Waters, Norman, Chakrabarti, Debopam, Doerig, Christian
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901647/
https://ncbi.nlm.nih.gov/pubmed/20305001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00005-10
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