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Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells

Engulfment of apoptotic cells occurs throughout life in multi-cellular organisms. Impaired apoptotic cell clearance (due to defective recognition/internalization or degradation) results in autoimmune disease1, 2. One fundamental challenge in understanding how defects in corpse removal translate into...

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Bibliographische Detailangaben
Hauptverfasser: Kinchen, Jason M., Ravichandran, Kodi S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901565/
https://ncbi.nlm.nih.gov/pubmed/20305638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08853
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