Homologous desensitization of guanylyl cyclase A, the receptor for atrial natriuretic peptide, is associated with a complex phosphorylation pattern

Atrial natriuretic peptide (ANP), via its guanylyl cyclase A (GC-A) receptor and intracellular guanosine 3′,5′-cyclic monophosphate production, is critically involved in the regulation of blood pressure. In patients with chronic heart failure, the plasma levels of ANP are increased, but the cardiova...

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Autores principales: Schröter, Juliane, Zahedi, René P, Hartmann, Michael, Gaßner, Birgit, Gazinski, Alexandra, Waschke, Jens, Sickmann, Albert, Kuhn, Michaela
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 2010
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901513/
https://ncbi.nlm.nih.gov/pubmed/20456499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2010.07658.x
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