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Retroviral Rem protein requires processing by signal peptidase and retrotranslocation for nuclear function

Mouse mammary tumor virus (MMTV) is a complex murine retrovirus that encodes an HIV Rev-like export protein, Rem, from a doubly spliced version of envelope (Env) mRNA. Previously, the N-terminal 98-amino acid sequence of Rem, which is identical to Env signal peptide (SP), and full-length Rem were sh...

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Detalhes bibliográficos
Main Authors: Byun, Hyewon, Halani, Nimita, Mertz, Jennifer A., Ali, Almas F., Lozano, Mary M., Dudley, Jaquelin P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901445/
https://ncbi.nlm.nih.gov/pubmed/20566871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004303107
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