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Effect of bilirubin on cytochrome c oxidase activity of mitochondria from mouse brain and liver

BACKGROUND: The unbound, free concentration (B(f)) of unconjugated bilirubin (UCB), and not the total UCB level, has been shown to correlate with bilirubin cytotoxicity, but the key molecular mechanisms accounting for the toxic effects of UCB are largely unknown. FINDINGS: Mouse liver mitochondria i...

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Detalhes bibliográficos
Main Authors: Malik, Safarina G, Irwanto, K Astrid, Ostrow, J Donald, Tiribelli, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901210/
https://ncbi.nlm.nih.gov/pubmed/20534120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-3-162
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